[This article belongs to Volume - 54, Issue - 02]
Gongcheng Kexue Yu Jishu/Advanced Engineering Science
Journal ID : AES-01-12-2022-014

Title : SEQUENCE ANALYSIS AND PHYLOGENETIC RELATIONSHIP OF COVID-19-WUHAN-HU-1
Farooqe E Azama,*, Nausheen Saba Khanamb , Aabsheen Saba Khanamc

Abstract :

A novel coronavirus associated with human-to-human transmission and severe human infection has been reported from Wuhan in China and spread worldwide. Our objectives were to characterize the genetic relationships of COVID-19-Wuhan-Hu-1 and some other coronaviruses. Viral diseases are widely spread infections caused by viruses, a type of microorganism. Viruses can cause a wide range of diseases and come in a variety of shapes and sizes. The most common type of viral illness is the common cold, which is caused by a viral infection of the upper respiratory tract. Bats have long been known to be natural reservoirs for a wide range of viruses. Bat coronaviruses have received special attention as one of the new coronaviruses that have produced unexpected human illness outbreaks around the world. COVID-19-Wuhan-Hu-1 was suggested to have originated from bats. Here we are going to find the phylogenetic relationship of COVID-19-Wuhan-Hu-1 with Pipistrellus Bat Coronavirus-HKU5, Human Coronavirus-NL63, Porcine Coronavirus-HKU15, Avian Infectious Bronchitisvirus-I, Beluga Whale Coronavirus-SW1, and Middle East Respiratory Syndrome Coronavirus. Evolutionary relationships are frequently described by phylogenetic trees, which are the most useful for genetic studies. We used a percent identity metric-based method for comparing trees, which extracts distinct alternative evolutionary relationships. Understanding the phylogenetic relationship of COVID-19-Wuhan-Hu-1 with other viruses is helpful for the prediction and prevention of another pandemic emergence in the future.