This research aims to investigate the frequency of magnetic impulses that disrupt the bio-electric signals produced during the cellular division of the Rift Valley Virus (Rvfv). For further analysis of the results, the experiment was expanded to an in vivo study in which mice were infected with Rvfv and were whole body exposed to square amplitude modulated waves (QAMW) that caused inhibition to the Rvfv. Previously inhibited Rvfv infected another group of animals, then the histological and biochemical of the liver were investigated for all the animal groups. The molecular structural changes in the liver were determined using dielectric relaxation tests in the frequency range of 100 kHz to 4.5 MHz. The results showed that after being exposed to the resonance frequency of 5.2 Hz Rvfv for 30 minutes, there was a highly significant reduction of cellular growth for Rvfv in addition to noticeable alterations in cellular morphology. When animals were infected with the Rift Valley virus (Rvfv) and subsequently exposed to QAMW throughout their bodies, histological and dielectric relaxation studies for the liver in mice revealed a considerable increase in liver health compared to the infected and non-exposed group. Furthermore, compared to animals with the untreated virus, the liver of animals infected with previously treated Rvfv (QAMW) displayed a significantly substantial decrease in cellular damage. Conclusion: Rvfv therapy at 5.2 Hz (QAMW) affects the biological activity and structure of the receptor, and it offers a promising way of regulating Rvfv activity in vivo applications.